Identify & connect
Map care and referral pathways. Work with healthcare providers, communities, and agreed outreach channels to reach potential participants.
Your strategic execution partner
Study successstarts withpeople.
We invest in the people closest to your study.
Better patient experiences. Stronger site teams. Greater study success.
Permanent TPS employeesDedicated to your programManaged by TPS
The Human Connection
When people are supported,
studies move forward.
Who TPS is
Global expertise.
Fully dedicated
to you.
Transformative Pharmaceutical Solutions is your strategic execution partner. We build and manage permanent, client-dedicated teams across patient recruitment, site execution and sponsor operations.
A managed service. A team with a team behind it.
You hand-select the people. TPS employs, integrates and manages them, with clinical, site, talent and relationship leaders supporting your program.
Custom-built teamsDirect site partnershipsSponsor-aligned delivery
Explore the scale and relationships behind TPS.
Permanent. Dedicated. Managed.How we build your team.
Built around you
Your strategy.
A team built to deliver.
We design the solution around your goals and current operating model. You hand-select the people. TPS manages the dedicated team.
You hand-select the team.
Experienced people.
Dedicated focus. Managed delivery.
Define success together.
Align on your goals, execution gaps and measures of success.
Define success together.
Align on your goals, execution gaps and measures of success.
Agree the goals, execution gaps, roles and measures that will shape your solution. We agree the scope, success measures, role mix, deployment and responsibilities around your operating model. A single study, related studies or a portfolio can each have a different solution.
Global talent. Custom fit.
Find experienced people matched to your roles and therapeutic needs.
Global talent. Custom fit.
Find experienced people matched to your roles and therapeutic needs.
Our global talent-acquisition team identifies, attracts, hires and deploys experienced people matched to your needs. The search is shaped around the actual work, therapeutic experience, location and required qualifications. Deployment timing depends on the roles, approvals, access and onboarding required.
IdentifyAttractHireDeploy
Your team. Fully dedicated.
You select the people. TPS employs them permanently.
Your team. Fully dedicated.
You select the people. TPS employs them permanently.
You select the people. We employ them permanently and dedicate them to your organization and goals. The team is custom-built for your engagement, not a preset roster. Within the agreed scope, its focus can span a study, a program of studies or your portfolio.
Integrate into the work.
Embed expertise into site workflows and sponsor operations.
Integrate into the work.
Embed expertise into site workflows and sponsor operations.
Direct site contracts and sponsor-aligned deployment put expertise where your strategy needs it. The principal investigator retains oversight of delegated activities. TPS manages its employees and service delivery. Sponsor decision authority, site delegation, training and authorized information access remain distinct.
Manage. Measure. Adapt.
Review progress together. Adapt support as priorities evolve.
Manage. Measure. Adapt.
Review progress together. Adapt support as priorities evolve.
Review progress together. Adjust agreed priorities and deployment as the study’s needs evolve. Operational insight informs decisions about the team, deployment and priorities. Changes follow the agreed scope, qualifications, site requirements and sponsor governance. Dedication to the client stays constant.
Built for the scale you need
A single studyA program of studiesYour portfolioProgram continuityHow support can follow a development program
Keep expertise connected across your program.
Related studies within one development program
Active study
→Next study
→Extension
Dedicated expertise. Protocol-specific responsibilities.
Your program
Related studies need continuity: retain operational learning, coordinate onboarding and keep expertise aligned to each protocol.
Our approach
Configure a dedicated TPS team across related protocols. Preserve protocol-specific training and delegation, coordinate agreed patient pathways, and review program priorities with the sponsor.
Continuity by design
A dedicated team can support an active study, a subsequent study and an extension, with protocol-specific training, delegation and responsibilities at every stage.
A program-level engagement is designed to retain expertise, carry learning forward and align support to the next development milestone.
The thinking behind TPSExperience that challenges the model.
Dan Perlman
Founder & Chief Executive Officer
The thinking behind the model
Dedicated people.A dedicated organization behind them.
Dan Perlman’s experience building clinical delivery models informs a simple TPS conviction: the people doing the work need committed leadership, practical support and a connection to the study’s goals.
Explore the founder storyThree Solution Frameworks
The right expertise.
Where it matters.
Find patients. Support your site partners. Strengthen your operations.
Choose a framework to explore the work.
A clearer path into research.Patient Recruitment Strategies
Find patients.
Build connections.
Identify and engage potential participants through everyday care, communities and referral pathways.
Explore the frameworkPatient Recruitment Strategies
Find where patients are.
Build their path into research.
When the right patients are not reaching the study.
Build a dedicated recruitment team around your study population, care pathways and referral opportunities. Connect patient interest with site-led assessment.
What TPS does
Educate & engage
Explain research opportunities, answer practical questions, and help people make an informed choice about taking the next step.
Navigate & follow through
Support referral follow-up and the handoff to site-led assessment, with agreed navigation and retention support.
Example roles Recruitment strategists. Patient Navigators. Outreach specialists.
A clearer route into research. Fewer avoidable gaps along the way.
More capacity. Better execution.Site Partner Clinical Operations
Reduce burden.
Strengthen execution.
Embed dedicated protocol expertise into site workflows, supporting the activities that keep studies moving.
Explore the frameworkSite Partner Clinical Operations
Act on behalf of the site.
Strengthen execution at the source.
When site workload is holding execution back.
Embed dedicated protocol expertise into the site’s working day. Agree the activities with the site and work under principal-investigator delegation.
What TPS does
Coordinate & support
Support agreed visits, study tasks, regulatory documentation, and communication. Work as an extension of the site team.
Capture & resolve
Support timely data entry, documentation, and query resolution. Surface recurring workflow issues where study data originate.
Engage & retain
Support authorized patient identification, scheduling, follow-up, and retention activities within the site's agreed scope.
Example roles Study Coordinators, Research Nurses, data and regulatory specialists, laboratory personnel, pharmacists, clinical raters and other qualified site roles.
More dedicated capacity. Less site burden. Quality built into execution.
Your operations. Fully supported.Sponsor Clinical Operations
Embed expertise.
Advance your goals.
Build a dedicated team within your organization, aligned to your systems, priorities and study goals.
Explore the frameworkSponsor Clinical Operations
Work within your team.
Turn study insight into action.
When your operations need focused capacity and continuity.
Build a permanent, dedicated TPS team around the sponsor functions you need, aligned to your systems, priorities and governance.
What TPS does
Plan & manage
Support study planning, timelines, deliverables, partners, and coordination within your operating model.
Monitor & improve
Support monitoring and quality activities under sponsor direction, informed by agreed patient and site operational insights.
Report & act
Bring together permitted information on recruitment, site activity, quality, and risks to support more informed study decisions.
Example roles Study leaders. CRAs. Clinical operations & quality specialists.
Better-informed decisions. Targeted support. Execution aligned to your study goals.
Powerful individually. Transformative together.
Discover TPS Connect™ Start with the framework you need. Together, they align patient access, site execution and sponsor decisions.
TPS Connect™
Our integrated operating model
Three frameworks. One connected model.
Stronger together.
By design.
TPS Connect™ aligns patient access, site execution and sponsor decisions through one managed operating model. Choose your priority to see how the work comes together.
Invest more where care happens.
Support patients. Empower sites. Advance the study.
Where does your study need momentum?
PATIENTS
Find. Educate.
Engage.
A supported path into research.
SITES
Enable. Execute.
Capture.
Quality where data are created.
SPONSOR OPERATIONS
See. Decide.
Deliver.
Sponsor-aligned action.
YOUR GOALS.
Studysuccess.
INSIGHT DECISIONS ACTION
One custom solution. Fully dedicated teams.
Connected around your study, program, or portfolio.
All three frameworks connected
One coordinated solution.
Patient opportunity becomes site action. Site insight informs sponsor decisions. Those decisions direct support back to the work.
See the patient, site and sponsor contributions
Accelerate enrollment
THE OPPORTUNITYPatient interest is there. The pathway into the study needs to work better.
PATIENT EXPERTISE
Find the right path.
Map care and referral pathways. Educate potential participants and support the next step into site-led assessment.
SITE EXPERTISE
Make sites ready.
Align delegated capacity, screening coordination, and follow-up so sites can act on the opportunity.
SPONSOR EXPERTISE
Turn insight into action.
Use agreed recruitment and capacity signals to redirect support toward the barriers that matter.
WHAT THIS ENABLESA clearer path from patient interest to study participation.
Build quality at the source
THE OPPORTUNITYRecurring data issues signal a need for stronger execution and targeted review.
PATIENT EXPERTISE
Support participation.
Help participants understand visit and reporting expectations, and identify practical barriers early.
SITE EXPERTISE
Build quality in.
Put protocol expertise into documentation, data entry, and query resolution within the site's agreed scope.
SPONSOR EXPERTISE
Act on the pattern.
Review permitted quality signals and coordinate targeted training, capacity, or process improvements.
WHAT THIS ENABLESStronger source execution. Earlier intervention. Less avoidable rework.
Reimagine oversight
THE OPPORTUNITYOversight becomes more useful when it is informed by the work as it happens.
PATIENT EXPERTISE
Surface barriers earlier.
Bring agreed engagement and follow-up insights into the operational discussion before gaps persist.
SITE EXPERTISE
Keep the work moving.
Support timely data, query follow-through, and monitoring readiness while preserving site oversight.
SPONSOR EXPERTISE
Focus oversight.
Use risk and quality signals to inform the sponsor's plan, including centralized, remote, and on-site activity where appropriate.
WHAT THIS ENABLESBetter-directed oversight and execution. Not less required oversight.
Explore the benefits and how the model is governed
BETTER FOR
Patients.
A clearer path. Support that stays.BETTER FOR
Sites.
Dedicated capacity. Stronger execution.BETTER FOR
Sponsors.
Actionable insight. Better-directed investment.BETTER FOR
Study success.
Connected expertise. Progress toward your goals.How the model is tailored and governed
TPS Connect™ brings your solution together around the role mix, deployment, information access and success measures agreed with you. TPS manages its employees and service delivery. Investigators retain oversight of delegated site activities, and sponsor decisions remain with the sponsor. Information is shared through authorized access and reporting. Monitoring follows the sponsor-approved, risk-based plan.
See the work behind the model.
Explore relevant TPS results, with the context of each engagement.Case studies / Impact in action
Real execution. Measurable impact.
Monitoring transformation
−35%Monitoring costs
+432%reported productivity increase
Lower costs.
Higher productivity.
35 resources · After one year
Explore the case study
U.S. patient enrollment
80%U.S. enrollment at TPS-supported sites
20%of U.S. sites supported by TPS
A focused footprint.
An outsized contribution.
Phase II oncology · U.S. study
Explore the case study
Site transformation
#2 & #15Enrollment rankings among 60 U.S. sites
2 siteswith no prior research experience
New to research.
Top U.S. enrollers.
Study-level site enablement
Explore the case study
Global patient enrollment
8%All study patients enrolled at those sites
1%of global sites supported by TPS
Small footprint.
Global contribution.
Phase III oncology · Global study
Explore the case study
Portfolio data quality
−53.6%Data-entry timeline
125protocol-site pairs analyzed
Earlier data.
Less query burden.
During support vs. before
Explore the case study
1 to 3 of 5 stories
The Partnership Voice
See what our partners say about us.
Confidence, every day
TPS was the one vendor I could always count on!
Your experienced team and dedicated management made it easy to “set it and forget it” knowing they’d exceed our study goals.
Global Study ManagerLarge Pharma A
Partnership at a critical milestone
“There is absolutely no way we could have done this without you.”
Senior DirectorLarge Pharma A
A shared focus on patients
“As we work together effectively, we are showing great benefit to our studies and most importantly to our patients.”
Global Study ManagerLarge Pharma A
Illustrative photography.
What could this kind of partnership make possible for your study?
Start a conversationYour goal is the starting point
Bring us the challenge.
Let’s build
the solution.
Recruitment momentum. Site capacity. Sponsor operations. Let’s explore where dedicated support can make a difference.
A useful first conversation
Your goal→Your current model→The right starting pointA model that fits your team
Do we need all Three Solution Frameworks?
No. Start with the environment and roles your strategy needs. TPS Connect™ describes the combined operating model when the frameworks work together; it is not a separate technology product or a mandatory package.
Can TPS work alongside our CRO and internal teams?
Yes. The solution is designed around your current organization, partners and priorities. We agree the work, interfaces and responsibilities together rather than requiring you to replace your existing operating model.
Who employs and directs the dedicated team?
TPS employs and manages its people and agreed service delivery. Delegated site activities remain under investigator oversight. Sponsor-side teams work within your systems, standard operating procedures and governance.
Make the conversation count.
Bring your priorities and relevant TPS stories together in a brief you can review and send.
Build my conversation brief
Your discussion brief
Selections stay in this tab until you send, copy or save your brief.
What to include
Your study goal. Where execution needs support. The team or geography you have in mind.
Your first conversation can start with a single study, a program or a portfolio.